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Type C retrovirus inactivation by human complement is determined by both the viral genome and the producer cell.

The inactivation of type C retroviruses by human serum may be a considerable impediment to the use of retroviral vectors in vivo for gene therapy. Here we show that virus inactivation is dependent both on the virus and on the cell line used to produce the virus. All viruses produced from murine NIH...

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Bibliografske podrobnosti
Main Authors: Takeuchi, Y, Cosset, F L, Lachmann, P J, Okada, H, Weiss, R A, Collins, M K
Format: Artigo
Jezik:Inglês
Izdano: 1994
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC237263/
https://ncbi.nlm.nih.gov/pubmed/7966590
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