Herpes simplex virus inhibits host cell splicing, and regulatory protein ICP27 is required for this effect.

While the majority of metazoan genes and those of the DNA viruses which infect them contain introns which require RNA splicing, herpes simplex virus type 1 (HSV-1) encodes relatively few spliced products. We previously showed that the HSV-1 immediate-early protein ICP27 decreased the levels of splic...

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Vydáno v:	J Virol
Hlavní autoři:	Hardy, W R, Sandri-Goldin, R M
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology (ASM) 1994
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC237240/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7966568/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.68.12.7790-7799.1994
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