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Alpha interferon-induced antiretroviral activities: restriction of viral nucleic acid synthesis and progeny virion production in human immunodeficiency virus type 1-infected monocytes.

Alpha interferon (IFN-alpha) restricts multiple steps of the human immunodeficiency virus type 1 (HIV-1) life cycle. A well-described effect of IFN-alpha is in the modulation of viral nucleic acid synthesis. We demonstrate that IFN-alpha influences HIV-1 DNA synthesis principally by reducing the pro...

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Publicat a:J Virol
Autors principals: Baca-Regen, L, Heinzinger, N, Stevenson, M, Gendelman, H E
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 1994
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC237202/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7933143/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.68.11.7559-7565.1994
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