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Sequence requirements for stable binding and function of Rep68 on the adeno-associated virus type 2 inverted terminal repeats.

Replication of the palindromic inverted terminal repeats (ITRs) of adeno-associated virus type 2 requires several functions of the viral nonstructural Rep proteins. These include binding to the ITR, nicking of the double-stranded replication intermediate at the terminal resolution site (trs), and th...

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Main Authors: Chiorini, J A, Wiener, S M, Owens, R A, Kyöstió, S R, Kotin, R M, Safer, B
Formato: Artigo
Idioma:Inglês
Publicado: 1994
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC237187/
https://ncbi.nlm.nih.gov/pubmed/7933128
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