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An amphipathic peptide from the C-terminal region of the human immunodeficiency virus envelope glycoprotein causes pore formation in membranes.

The peptide fragment of the carboxy-terminal region of the human immunodeficiency virus (HIV) transmembrane protein (gp41) has been implicated in T-cell death. This positively charged, amphipathic helix (amino acids 828 to 848) of the envelope protein is located within virions or cytoplasm. We studi...

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Udgivet i:J Virol
Principais autores: Chernomordik, L, Chanturiya, A N, Suss-Toby, E, Nora, E, Zimmerberg, J
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1994
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC237150/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7933093/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.68.11.7115-7123.1994
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