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Vaccines prepared from chimeras of foot-and-mouth disease virus (FMDV) induce neutralizing antibodies and protective immunity to multiple serotypes of FMDV.

The G-H loop of VP1 (residues 132 to 159) of foot-and-mouth disease virus (FMDV) is a prominent feature on the virion surface and has an important role in vaccine efficacy, generation of antigenic variants, and cell binding. Using an infectious cDNA of FMDV, we have constructed serotype A viruses in...

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Detalhes bibliográficos
Publicado no:J Virol
Principais autores: Rieder, E, Baxt, B, Lubroth, J, Mason, P W
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1994
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC237147/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7523697/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.68.11.7092-7098.1994
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