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A partially attenuated simian immunodeficiency virus induces host immunity that correlates with resistance to pathogenic virus challenge.

Three infectious, attenuated molecular clones of simian immunodeficiency virus (SIVmac) were tested for viral and host determinants of protective immunity. The viruses differed in degree of virulence from highly attenuated to moderately attenuated to partially attenuated. Levels of immune stimulatio...

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Detalhes bibliográficos
Publicado no:J Virol
Principais autores: Lohman, B L, McChesney, M B, Miller, C J, McGowan, E, Joye, S M, Van Rompay, K K, Reay, E, Antipa, L, Pedersen, N C, Marthas, M L
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1994
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC237139/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7933084/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.68.11.7021-7029.1994
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