La autoantigen alleviates translational repression by the 5' leader sequence of the human immunodeficiency virus type 1 mRNA.

The trans-activation response element (TAR) at the 5' end of the human immunodeficiency virus type 1 (HIV-1) mRNAs forms a stable hairpin structure which is a target for binding of the virally encoded protein Tat, which activates viral gene expression, as well as several cellular factors. TAR i...

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Bibliographic Details
Published in:J Virol
Main Authors: Svitkin, Y V, Pause, A, Sonenberg, N
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1994
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC237137/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7933082/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.68.11.7001-7007.1994
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