Efficient particle formation can occur if the matrix domain of human immunodeficiency virus type 1 Gag is substituted by a myristylation signal.

Lentiviruses, such as human immunodeficiency virus type 1 (HIV-1), assemble at and bud through the cytoplasmic membrane. Both the matrix (MA) domain of Gag and its amino-terminal myristylation have been implicated in these processes. We have created HIV-1 proviruses lacking the entire matrix domain...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Lee, P P, Linial, M L
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1994
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC237085/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7521919/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.68.10.6644-6654.1994
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