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Effects of human chromosome 12 on interactions between Tat and TAR of human immunodeficiency virus type 1.

Rates of transcriptions of the human immunodeficiency virus are greatly increased by the viral trans activator Tat. In vitro, Tat binds to the 5' bulge of the trans-activation response (TAR) RNA stem-loop, which is present in all viral transcripts. In human cells, the central loop in TAR and it...

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Main Authors: Alonso, A, Cujec, T P, Peterlin, B M
Formato: Artigo
Idioma:Inglês
Publicado: 1994
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC237071/
https://ncbi.nlm.nih.gov/pubmed/8083988
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