The role of upstream U3 sequences in the pathogenesis of simian immunodeficiency virus-induced AIDS in rhesus monkeys.

The nef reading frame overlaps about 70% of the U3 region of the 3' long terminal repeat (LTR) in primate lentiviruses. We investigated the functional role of these overlapping U3 sequences by analyzing the properties of three mutant forms of the pathogenic SIVmac239 clone. In mutant UScon, 90 of 27...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Ilyinskii, P O, Daniel, M D, Simon, M A, Lackner, A A, Desrosiers, R C
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1994
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC236999/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7914551/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.68.9.5933-5944.1994
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