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Severe reduction in leukocyte adhesion and monocyte extravasation in mice deficient in CC chemokine receptor 2

CC chemokine receptor 2 (CCR2) is a prominent receptor for the monocyte chemoattractant protein (MCP) group of CC chemokines. Mice generated by gene targeting to lack CCR2 exhibit normal leukocyte rolling but have a pronounced defect in MCP-1-induced leukocyte firm adhesion to microvascular endothel...

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Detalhes bibliográficos
Main Authors: Kuziel, William A., Morgan, Sharon J., Dawson, Tracey C., Griffin, Stephanie, Smithies, Oliver, Ley, Klaus, Maeda, Nobuyo
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences of the USA 1997
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC23699/
https://ncbi.nlm.nih.gov/pubmed/9342361
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