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Identification of terminal adenylyl transferase activity of the poliovirus polymerase 3Dpol.

A terminal adenylyl transferase (TATase) activity has been identified in preparations of purified poliovirus RNA-dependent RNA polymerase (3Dpol). Highly purified 3Dpol is capable of adding [32P]AMP to the 3' ends of chemically synthesized 12-nucleotide (nt)-long RNAs. The purified 52-kDa polypeptid...

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Détails bibliographiques
Publié dans:J Virol
Auteurs principaux: Neufeld, K L, Galarza, J M, Richards, O C, Summers, D F, Ehrenfeld, E
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 1994
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC236985/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8057462/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.68.9.5811-5818.1994
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