Myristylation of Pr60gag of the murine AIDS-defective virus is required to induce disease and notably for the expansion of its target cells.

Murine AIDS (MAIDS) is characterized by severe lymphadenopathy and splenomegaly. The proliferation of the infected target B cells is also an important manifestation of the disease (M. Huang, C. Simard, D. G. Kay, and P. Jolicoeur, J. Virol. 65:6562-6571, 1991). The etiologic agent of MAIDS is a defe...

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Bibliografiske detaljer

Udgivet i:	J Virol
Principais autores:	Huang, M, Jolicoeur, P
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 1994
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC236966/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8057445/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.68.9.5648-5655.1994
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