The kinetics of simian virus 40-induced progression of quiescent cells into S phase depend on four independent functions of large T antigen.

Microinjection of purified simian virus 40 large-T-antigen protein or DNA encoding T antigen into serum-starved cells stimulates them to re-enter the cell cycle and progress through G1 into the S phase. Genetic analysis of T antigen indicated that neither its Rb/p107-binding activity nor its p53-bin...

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Detalhes bibliográficos
Main Authors: Dickmanns, A, Zeitvogel, A, Simmersbach, F, Weber, R, Arthur, A K, Dehde, S, Wildeman, A G, Fanning, E
Formato: Artigo
Idioma:Inglês
Publicado em: 1994
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC236950/
https://ncbi.nlm.nih.gov/pubmed/8057432
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