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The kinetics of simian virus 40-induced progression of quiescent cells into S phase depend on four independent functions of large T antigen.

Microinjection of purified simian virus 40 large-T-antigen protein or DNA encoding T antigen into serum-starved cells stimulates them to re-enter the cell cycle and progress through G1 into the S phase. Genetic analysis of T antigen indicated that neither its Rb/p107-binding activity nor its p53-bin...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Dickmanns, A, Zeitvogel, A, Simmersbach, F, Weber, R, Arthur, A K, Dehde, S, Wildeman, A G, Fanning, E
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1994
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC236950/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8057432/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.68.9.5496-5508.1994
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