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The kinetics of simian virus 40-induced progression of quiescent cells into S phase depend on four independent functions of large T antigen.
Microinjection of purified simian virus 40 large-T-antigen protein or DNA encoding T antigen into serum-starved cells stimulates them to re-enter the cell cycle and progress through G1 into the S phase. Genetic analysis of T antigen indicated that neither its Rb/p107-binding activity nor its p53-bin...
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| Publicado no: | J Virol |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
1994
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC236950/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8057432/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.68.9.5496-5508.1994 |
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