Glycosylphosphatidylinositol-anchored CD4 supports human immunodeficiency virus type 1 replication, but not cytopathic effect, in T-cell transfectants.

Despite equivalent p24 antigen production, HSB-2 T cells expressing glycosylphosphatidylinositol (GPi)-linked CD4 were productively infected without cell death or syncytium formation, unlike HSB-2 transfectants expressing wild-type CD4 (wtCD4). HSB-2 transfectants dually expressing wtCD4 and GPi-lin...

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Detalhes bibliográficos
Main Authors: Marshall, W L, Mittler, E S, Avery, P, Lawrence, J P, Finberg, R W
Formato: Artigo
Idioma:Inglês
Publicado em: 1994
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC236913/
https://ncbi.nlm.nih.gov/pubmed/8189539
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