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Identification of a sequence in the unique 5' open reading frame of the gene encoding glycosylated Gag which influences the incubation period of neurodegenerative disease induced by a murine retrovirus.

Neonatal inoculation of the wild-mouse ecotropic retrovirus CasBrE (clone 15-1) causes a noninflammatory spongiform neurodegenerative disease with an incubation period of > or = 6 months. Introduction of sequences from Friend murine leukemia virus (clone FB29) into the genome of CasBrE results in a...

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Détails bibliographiques
Publié dans:J Virol
Auteurs principaux: Portis, J L, Spangrude, G J, McAtee, F J
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 1994
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC236893/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8189525/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.68.6.3879-3887.1994
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