Products of the porcine group C rotavirus NSP3 gene bind specifically to double-stranded RNA and inhibit activation of the interferon-induced protein kinase PKR.

The porcine group C rotavirus (Cowden strain) NSP3 protein (the group C equivalent of the group A gene 7 product, formerly called NS34) shares homology with known double-stranded RNA-binding proteins, such as the interferon-induced, double-stranded RNA-dependent protein kinase PKR. A clone of NSP3,...

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Detalles Bibliográficos
Publicado en:J Virol
Main Authors: Langland, J O, Pettiford, S, Jiang, B, Jacobs, B L
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 1994
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC236887/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7514679/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.68.6.3821-3829.1994
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