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The exo- or endonucleolytic preference of bovine pancreatic ribonuclease A depends on its subsites structure and on the substrate size

The cleavage pattern of oligocytidylic acid substrates by bovine pancreatic ribonuclease A (RNase A) was studied by means of reversed-phase HPLC. Oligocytidylic acids, ranging from dinucleotides to heptanucleotides, were obtained by RNase A digestion of poly(C). They were identified by MALDI-TOF mas...

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書誌詳細
主要な著者: Cuchillo, Claudi M., Moussaoui, Mohamed, Barman, Tom, Travers, Franck, Nogués, M. Victòria
フォーマット: Artigo
言語:Inglês
出版事項: Cold Spring Harbor Laboratory Press 2002
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2368780/
https://ncbi.nlm.nih.gov/pubmed/11742128
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