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MLCK-A, an unconventional myosin light chain kinase from Dictyostelium, is activated by a cGMP-dependent pathway

Dictyostelium myosin II is activated by phosphorylation of its regulatory light chain by myosin light chain kinase A (MLCK-A), an unconventional MLCK that is not regulated by Ca(2+)/calmodulin. MLCK-A is activated by autophosphorylation of threonine-289 outside of the catalytic domain and by phospho...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Silveira, Linda A., Smith, Janet L., Tan, John L., Spudich, James A.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1998
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC23685/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9789030/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.22.13000
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