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Alteration of V3 loop context within the envelope of human immunodeficiency virus type 1 enhances neutralization.

Neutralization of a chimeric human immunodeficiency virus (HIV) type 1, containing the V3 loop of the MN isolate substituted within the HXB2 envelope, was enhanced up to 20-fold compared with the HXB2 or MN parental isolates by human HIV-positive sera. MN V3 loop-specific monoclonal antibodies were...

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Autors principals: Robert-Guroff, M, Louie, A, Myagkikh, M, Michaels, F, Kieny, M P, White-Scharf, M E, Potts, B, Grogg, D, Reitz, M S
Format: Artigo
Idioma:Inglês
Publicat: 1994
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC236848/
https://ncbi.nlm.nih.gov/pubmed/7514675
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