Discrepancy between infectivity and antigenicity stabilization of oral poliovirus vaccine by a capsid-binding compound.

Two hundred forty pyridazinamine derivatives were tested for the ability to stabilize the antigenicity and infectivity of oral poliovirus vaccine subjected to 45 degrees C for 2 h. Seven compounds stabilized the antigenicity of all three vaccine strains and neutralized the viral particles in a way t...

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Veröffentlicht in:	J Virol
Hauptverfasser:	Andries, K, Rombaut, B, Dewindt, B, Boeyé, A
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1994
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC236833/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8151800/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.68.5.3397-3400.1994
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