Induction of a major histocompatibility complex class I-restricted cytotoxic T-lymphocyte response to a highly conserved region of human immunodeficiency virus type 1 (HIV-1) gp120 in seronegative humans immunized with a candidate HIV-1 vaccine.

Efforts to induce broadly reactive immunity against human immunodeficiency virus type 1 (HIV-1) have been impaired by the extent of sequence variation exhibited by this lentivirus. Cytotoxic T lymphocytes (CTL) specific for other viruses such as influenza virus have been shown to mediate immunity ag...

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Dettagli Bibliografici
Pubblicato in:J Virol
Autori principali: Johnson, R P, Hammond, S A, Trocha, A, Siliciano, R F, Walker, B D
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 1994
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC236805/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7908700/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.68.5.3145-3153.1994
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