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Hepadnavirus P protein utilizes a tyrosine residue in the TP domain to prime reverse transcription.

Hepadnavirus DNA minus strands are covalently linked at their 5' terminus to the viral P gene product, which has been taken to indicate that the hepadnaviral polymerase polypeptide itself also functions as a protein primer for initiating reverse transcription of the RNA pregenome. The present study...

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Bibliographic Details
Published in:J Virol
Main Authors: Weber, M, Bronsema, V, Bartos, H, Bosserhoff, A, Bartenschlager, R, Schaller, H
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1994
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC236789/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7512155/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.68.5.2994-2999.1994
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