Elements distinct from human immunodeficiency virus type 1 splice sites are responsible for the Rev dependence of env mRNA.

In the absence of the viral regulatory protein Rev, the human immunodeficiency virus type 1 gag/pol and env mRNAs are inefficiently expressed, since nucleocytoplasmic transport, stability, and polysomal loading are impaired. It has been suggested that splicing is necessary for Rev function and that...

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Main Authors: Nasioulas, G, Zolotukhin, A S, Tabernero, C, Solomin, L, Cunningham, C P, Pavlakis, G N, Felber, B K
Formato: Artigo
Idioma:Inglês
Publicado: 1994
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC236788/
https://ncbi.nlm.nih.gov/pubmed/8151769
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