Human cytomegalovirus maturational proteinase: expression in Escherichia coli, purification, and enzymatic characterization by using peptide substrate mimics of natural cleavage sites.

The proteolytic processing of the human cytomegalovirus (HCMV) assembly protein, resulting in truncation of its C terminus, is an essential step in virion maturation. The proteinase responsible for this cleavage is the amino-terminal half of the protein encoded by the UL80a open reading fame. We hav...

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Main Authors: Burck, P J, Berg, D H, Luk, T P, Sassmannshausen, L M, Wakulchik, M, Smith, D P, Hsiung, H M, Becker, G W, Gibson, W, Villarreal, E C
Format: Artigo
Sprog:Inglês
Udgivet: 1994
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC236782/
https://ncbi.nlm.nih.gov/pubmed/8151764
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