Human cytomegalovirus maturational proteinase: expression in Escherichia coli, purification, and enzymatic characterization by using peptide substrate mimics of natural cleavage sites.

The proteolytic processing of the human cytomegalovirus (HCMV) assembly protein, resulting in truncation of its C terminus, is an essential step in virion maturation. The proteinase responsible for this cleavage is the amino-terminal half of the protein encoded by the UL80a open reading fame. We hav...

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Detalhes bibliográficos
Main Authors: Burck, P J, Berg, D H, Luk, T P, Sassmannshausen, L M, Wakulchik, M, Smith, D P, Hsiung, H M, Becker, G W, Gibson, W, Villarreal, E C
Formato: Artigo
Idioma:Inglês
Publicado em: 1994
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC236782/
https://ncbi.nlm.nih.gov/pubmed/8151764
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