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Stabilization of the tumor suppressor p53 during cellular transformation by simian virus 40: influence of viral and cellular factors and biological consequences.

To understand the process and biological significance of metabolic stabilization of p53 during simian virus 40 (SV40)-induced cellular transformation, we analyzed cellular and viral parameters involved in this process. We demonstrate that neither large T expression as such nor the cellular phenotype...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Tiemann, F, Deppert, W
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1994
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC236775/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8151757/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.68.5.2869-2878.1994
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