Circulating anti-Tax cytotoxic T lymphocytes from human T-cell leukemia virus type I-infected people, with and without tropical spastic paraparesis, recognize multiple epitopes simultaneously.

CD8+ T cells were freshly isolated from a human T-cell leukemia virus type I (HTLV-I)-infected patient with tropical spastic paraparesis. These cells, which were specific for HTLV-I Tax, simultaneously recognized a minimum of five, and possibly as many as seven, distinct peptide epitopes within the...

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Detalles Bibliográficos
Publicado en:J Virol
Autores principales: Parker, C E, Nightingale, S, Taylor, G P, Weber, J, Bangham, C R
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 1994
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC236774/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7512153/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.68.5.2860-2868.1994
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