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Statistical corrections of linkage data suggest predominantly cis regulations of gene expression

Morley et al. (Nature 2004, 430:743–747) detected significant linkages to the expression levels of 142 genes (of 3554) at a reported threshold of genome-wide p = 0.001 (LOD ≈ 5.3), using 14 three-generation Centre d'Etude du Polymorphisme Humain pedigrees. Most of the linkages (77%) were trans,...

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Détails bibliographiques
Auteurs principaux: Shi, Jianxin, Siegmund, David O, Levinson, Douglas F
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2007
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2367613/
https://ncbi.nlm.nih.gov/pubmed/18466489
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