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Two-stage approach for identifying single-nucleotide polymorphisms associated with rheumatoid arthritis using random forests and Bayesian networks

We used the simulated data set from Genetic Analysis Workshop 15 Problem 3 to assess a two-stage approach for identifying single-nucleotide polymorphisms (SNPs) associated with rheumatoid arthritis (RA). In the first stage, we used random forests (RF) to screen large amounts of genetic data using th...

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Detalhes bibliográficos
Main Authors: Meng, Yan, Yang, Qiong, Cuenco, Karen T, Cupples, L Adrienne, DeStefano, Anita L, Lunetta, Kathryn L
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2367609/
https://ncbi.nlm.nih.gov/pubmed/18466556
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