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Impact of normalization and filtering on linkage analysis of gene expression data

Using the Problem 1 data set made available for Genetic Analysis Workshop 15, we assessed sensitivity of linkage results to a correlation-based feature extraction method as well as to different normalization procedures applied to the raw Affymetrix gene expression microarray data. The impact of thes...

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Hlavní autoři: Beyene, Joseph, Hu, Pingzhao, Parkhomenko, Elena, Tritchler, David
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2367572/
https://ncbi.nlm.nih.gov/pubmed/18466495
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