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Linkage, case-control association, and family-based association tests for complex disorders

We carried out an analysis of the Genetic Analysis Workshop 15 simulated Problem 3 data. We restricted ourselves to the present/absent phenotype. Linkage analysis revealed a very strong signal on chromosome 6. Association analysis revealed additional susceptible loci located on chromosomes 11 and 18...

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Autors principals: Suarez, Brian K, Culverhouse, Robert, Jin, Carol H, Hinrichs, Anthony
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2367550/
https://ncbi.nlm.nih.gov/pubmed/18466542
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