Comparison of affected sibling-pair linkage methods to identify gene × gene interaction in GAW15 simulated data

Non-parametric linkage methods have had limited success in detecting gene by gene interactions. Using affected sibling-pair (ASP) data from all replicates of the simulated data from Problem 3, we assessed the statistical power of three approaches to identify the gene × gene interaction between two l...

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Hlavní autoři: Larkin, Emma K, Morris, Nathan J, Li, Yali, Nock, Nora L, Stein, Catherine M
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2007
Témata:
Proceedings
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2367530/
https://ncbi.nlm.nih.gov/pubmed/18466567
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