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Joint analysis of case-parents trio and unrelated case-control designs in large scale association studies

We present a new method for testing association when data from both case-parents trios and unrelated controls are available. Our method combines test statistics for case-parents trio and unrelated case-control studies by adjusting for the correlation that arises when the same set of cases is used fo...

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Detalhes bibliográficos
Main Authors: Joo, Jungnam, Tian, Xin, Zheng, Gang, Stylianou, Mario, Lin, Jing-Ping, Geller, Nancy L
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2367524/
https://ncbi.nlm.nih.gov/pubmed/18466525
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