Regulation of endocytic recycling by C. elegans Rab35 and its regulator RME-4, a coated-pit protein

Using Caenorhabditis elegans genetic screens, we identified receptor-mediated endocytosis (RME)-4 and RME-5/RAB-35 as important regulators of yolk endocytosis in vivo. In rme-4 and rab-35 mutants, yolk receptors do not accumulate on the plasma membrane as would be expected in an internalization muta...

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Main Authors: Sato, Miyuki, Sato, Ken, Liou, Willisa, Pant, Saumya, Harada, Akihiro, Grant, Barth D
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2008
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2367398/
https://ncbi.nlm.nih.gov/pubmed/18354496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2008.54
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