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Regulation of endocytic recycling by C. elegans Rab35 and its regulator RME-4, a coated-pit protein
Using Caenorhabditis elegans genetic screens, we identified receptor-mediated endocytosis (RME)-4 and RME-5/RAB-35 as important regulators of yolk endocytosis in vivo. In rme-4 and rab-35 mutants, yolk receptors do not accumulate on the plasma membrane as would be expected in an internalization muta...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2367398/ https://ncbi.nlm.nih.gov/pubmed/18354496 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2008.54 |
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