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Temperature-sensitive mutations in the gene encoding the small subunit of the vaccinia virus early transcription factor impair promoter binding, transcription activation, and packaging of multiple virion components.

The vaccinia virus D6R open reading frame encodes the small subunit of the heterodimeric vaccinia virus early transcription factor (VETF) that activates transcription of early genes in vitro. VETF binds early gene promoters and has a DNA-dependent ATPase activity that is essential for activation of...

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Bibliografiske detaljer
Udgivet i:J Virol
Main Authors: Li, J, Pennington, M J, Broyles, S S
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1994
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC236738/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8139039/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.68.4.2605-2614.1994
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