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Epistatic Interaction Between the K-Homology Domain Protein HEK2 and SIR1 at HMR and Telomeres in Yeast

In budding yeast, telomeres, the ribosomal DNA array, and HM loci are transcriptionally silenced by chromatin complexes containing Sir proteins. Hek2, a protein containing three evolutionary conserved RNA-binding K-homology domains, was identified as a suppressor of telomeric silencing [telomeric po...

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Autores principales: Denisenko, Oleg, Bomsztyk, Karol
Formato: Artigo
Lenguaje:Inglês
Publicado: 2007
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2367324/
https://ncbi.nlm.nih.gov/pubmed/18067921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2007.11.001
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