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Caged Agonist of P2Y(1) and P2Y(12) Receptors for Light-Directed Facilitation of Platelet Aggregation
We have prepared a caged form (MRS2703) of a potent dual agonist of the P2Y(1) and P2Y(12) nucleotide receptors, 2-MeSADP, by blocking the β-phosphate group with a 1-(3,4-dimethyloxyphenyl)eth-1-yl phosphoester. Although MRS2703 is itself inactive at human P2Y(1) and P2Y(12) receptors expressed hete...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2367217/ https://ncbi.nlm.nih.gov/pubmed/18199424 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2007.10.037 |
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