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Two functional domains of the influenza virus NS1 protein are required for regulation of nuclear export of mRNA.

The influenza virus NS1 protein is the only known example of a protein that inhibits the nuclear export of mRNA. To identify the functional domains of this protein, we introduced 18 2- or 3-amino-acid substitutions at approximately equally spaced locations along the entire length of the protein. Two...

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Библиографические подробности
Опубликовано в::J Virol
Главные авторы: Qian, X Y, Alonso-Caplen, F, Krug, R M
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology (ASM) 1994
Предметы:
Online-ссылка:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC236721/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8139028/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.68.4.2433-2441.1994
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