Functional role of the V1/V2 region of human immunodeficiency virus type 1 envelope glycoprotein gp120 in infection of primary macrophages and soluble CD4 neutralization.

We have examined the influence of the V1/V2 region of the human immunodeficiency virus type 1 (HIV-1) gp120 on certain biologic properties of the virus. We observed that on the genomic background of the T-cell-line-tropic strain, HIV-1SF2mc, both the V1 and V2 domains of the macrophage-tropic strain...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Koito, A, Harrowe, G, Levy, J A, Cheng-Mayer, C
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1994
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC236701/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8139010/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.68.4.2253-2259.1994
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