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Water and urea interactions with the native and unfolded forms of a β-barrel protein

A fundamental understanding of protein stability and the mechanism of denaturant action must ultimately rest on detailed knowledge about the structure, solvation, and energetics of the denatured state. Here, we use (17)O and (2)H magnetic relaxation dispersion (MRD) to study urea-induced denaturatio...

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Détails bibliographiques
Auteurs principaux: Modig, Kristofer, Kurian, Elizabeth, Prendergast, Franklyn G., Halle, Bertil
Format: Artigo
Langue:Inglês
Publié: Cold Spring Harbor Laboratory Press 2003
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2366985/
https://ncbi.nlm.nih.gov/pubmed/14627737
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