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Water and urea interactions with the native and unfolded forms of a β-barrel protein

A fundamental understanding of protein stability and the mechanism of denaturant action must ultimately rest on detailed knowledge about the structure, solvation, and energetics of the denatured state. Here, we use (17)O and (2)H magnetic relaxation dispersion (MRD) to study urea-induced denaturatio...

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Detalhes bibliográficos
Main Authors: Modig, Kristofer, Kurian, Elizabeth, Prendergast, Franklyn G., Halle, Bertil
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2366985/
https://ncbi.nlm.nih.gov/pubmed/14627737
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