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Constraints on the conformation of the cytoplasmic face of dark-adapted and light-excited rhodopsin inferred from antirhodopsin antibody imprints

Rhodopsin is the best-understood member of the large G protein–coupled receptor (GPCR) superfamily. The G-protein amplification cascade is triggered by poorly understood light-induced conformational changes in rhodopsin that are homologous to changes caused by agonists in other GPCRs. We have applie...

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Detalhes bibliográficos
Main Authors: Bailey, Brian W., Mumey, Brendan, Hargrave, Paul A., Arendt, Anatol, Ernst, Oliver P., Hofmann, Klaus Peter, Callis, Patrik R., Burritt, James B., Jesaitis, Algirdas J., Dratz, Edward A.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2003
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2366960/
https://ncbi.nlm.nih.gov/pubmed/14573859
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