Deletion of Many Yeast Introns Reveals a Minority of Genes that Require Splicing for Function

Splicing regulates gene expression and contributes to proteomic diversity in higher eukaryotes. However, in yeast only 283 of the 6000 genes contain introns and their impact on cell function is not clear. To assess the contribution of introns to cell function, we initiated large-scale intron deletio...

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Main Authors: Parenteau, Julie, Durand, Mathieu, Véronneau, Steeve, Lacombe, Andrée-Anne, Morin, Geneviève, Guérin, Valérie, Cecez, Bojana, Gervais-Bird, Julien, Koh, Chu-Shin, Brunelle, David, Wellinger, Raymund J., Chabot, Benoit, Abou Elela, Sherif
Format: Artigo
Language:Inglês
Published: The American Society for Cell Biology 2008
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2366882/
https://ncbi.nlm.nih.gov/pubmed/18287520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E07-12-1254
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