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The Hypolipidemic Activity of Heterocyclic Thiosemicarbazones, Thioureas and Their Metal Complexes in Sprague Dawley Male Rats

Heterocyclic thiosemicarbazones, thioureas and their copper, nickel, and cobalt complexes were shown to be potent hypolipidemic agents in male Sprague Dawley rats at 8 mg/kg/day, orally. These agents lowered the activity of rat hepatic rate limiting enzymes for the synthesis of cholesterol and trigl...

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Autors principals: Hall, Iris H., Chen, S. Y., Barnes, Betsy Jo, West, Douglas X.
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 1999
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2366827/
https://ncbi.nlm.nih.gov/pubmed/18472903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/MBD.1999.143
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