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Reduced nuclear import of human immunodeficiency virus type 1 preintegration complexes in the presence of a prototypic nuclear targeting signal.

Nuclear import of the retroviral preintegration complex and integration of retroviral with host cell DNA are essential steps for completion of the virus life cycle. The preintegration complex of the lentivirus human immunodeficiency virus type 1 (HIV-1) displays karyophilic properties and, as a cons...

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Detalhes bibliográficos
Publicado no:J Virol
Principais autores: Gulizia, J, Dempsey, M P, Sharova, N, Bukrinsky, M I, Spitz, L, Goldfarb, D, Stevenson, M
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1994
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC236670/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8107265/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.68.3.2021-2025.1994
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