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Function of the cytoplasmic domain of a retroviral transmembrane protein: p15E-p2E cleavage activates the membrane fusion capability of the murine leukemia virus Env protein.

In the murine leukemia viruses (MuLVs), the Env complex is initially cleaved by a cellular protease into gp70SU and pre15ETM. After the virus particle is released from the cell, the C-terminal 16 residues are removed from the cytoplasmic domain of pre15E by the viral protease, yielding the mature p1...

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Detalhes bibliográficos
Publicado no:J Virol
Principais autores: Rein, A, Mirro, J, Haynes, J G, Ernst, S M, Nagashima, K
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1994
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC236638/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8107239/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.68.3.1773-1781.1994
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