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Liver-Specific Hepatocyte Nuclear Factor-4α Deficiency: Greater Impact on Gene Expression in Male than in Female Mouse Liver
Hepatocyte nuclear factor (HNF)-4α is a liver-enriched transcription factor that regulates numerous liver-expressed genes including several sex-specific cytochrome P450 genes. Presently, a liver-specific HNF4α-deficient mouse model was used to characterize the impact of liver HNF4α deficiency on a g...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Endocrine Society
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2366185/ https://ncbi.nlm.nih.gov/pubmed/18276827 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2007-0564 |
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