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Liver-Specific Hepatocyte Nuclear Factor-4α Deficiency: Greater Impact on Gene Expression in Male than in Female Mouse Liver

Hepatocyte nuclear factor (HNF)-4α is a liver-enriched transcription factor that regulates numerous liver-expressed genes including several sex-specific cytochrome P450 genes. Presently, a liver-specific HNF4α-deficient mouse model was used to characterize the impact of liver HNF4α deficiency on a g...

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Detalles Bibliográficos
Main Authors: Holloway, Minita G., Miles, Gregory D., Dombkowski, Alan A., Waxman, David J.
Formato: Artigo
Idioma:Inglês
Publicado: The Endocrine Society 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2366185/
https://ncbi.nlm.nih.gov/pubmed/18276827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2007-0564
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