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Mast Cell α and β Tryptases Changed Rapidly during Primate Speciation and Evolved from γ-Like Transmembrane Peptidases in Ancestral Vertebrates

Human mast cell tryptases vary strikingly in secretion, catalytic competence, and inheritance. To explore the basis of variation, we compared genes from a range of primates, including humans, great apes (chimpanzee, gorilla, orangutan), Old- and New-World monkeys (macaque and marmoset), and a prosim...

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Bibliografiske detaljer
Main Authors: Trivedi, Neil N., Tong, Qiao, Raman, Kavita, Bhagwandin, Vikash J., Caughey, George H.
Format: Artigo
Sprog:Inglês
Udgivet: 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2366170/
https://ncbi.nlm.nih.gov/pubmed/17947681
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