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Engineered Lentivector Targeting of Dendritic Cells for In Vivo Immunization
We report a method of inducing antigen production in dendritic cells (DCs) by in vivo targeting with lentiviral vectors that specifically bind to the DC surface protein, DC-SIGN. To target the DCs, the lentivector was enveloped with a viral glycoprotein from Sindbis virus, engineered to be DC-SIGN-s...
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| Main Authors: | , , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2366162/ https://ncbi.nlm.nih.gov/pubmed/18297056 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt1390 |
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