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Folate and One-Carbon Metabolism Gene Polymorphisms and Their Associations With Oral Facial Clefts

Folate metabolism plays a critical role in embryonic development. Prenatal folate supplementation reduces the risk of neural tube defects and probably oral facial clefts. Previous studies of related metabolic genes have associated polymorphisms in cystathionine-beta-synthase (CBS) and 5,10-methylene...

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Detalhes bibliográficos
Main Authors: Boyles, Abee L., Wilcox, Allen J., Taylor, Jack A., Meyer, Klaus, Fredriksen, Åse, Ueland, Per Magne, Drevon, Christian A., Vollset, Stein Emil, Lie, Rolv Terje
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2366099/
https://ncbi.nlm.nih.gov/pubmed/18203168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ajmg.a.32162
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